Endothelin Antagonists may be a Treatment Option for Cardiac Syndrome X, or Not ?

AdipoRon may be benefit for atherosclerosis prevention

Atherosclerosis has serious role in coronary arteries disease,so it is important to establish effective strategies for prevention or even treatment of atherosclerosis. Adiponectin, as one of the most abundant adipokines, has insulin sensitivity, anti-inflammatory and anti-atherogenic properties. Disturbed adiponectin actions through its receptor, (AdipoR1 and AdipoR2) may be involved in atheros...

Vasopressin, not octreotide, may be beneficial in the treatment of hepatorenal syndrome: a retrospective study.

BACKGROUND Hepatorenal syndrome (HRS) is a severe complication of cirrhosis and is associated with high mortality. Ornipressin and terlipressin are effective in treatment of HRS, but are not available in the USA. The efficacy of vasopressin (AVP) and octreotide (OCT) infusions, commonly utilized in the USA, in the treatment of HRS is unknown. This study aims to evaluate the effects of AVP and O...

Exhaustion or fatigability may not only be cardiac but also myopathic

ventricular block, left bundle branch block, or QT prolonga-tion [5]. Easy fatigability or exhaustion may not only be a cardiac symptom but may also be a clinical manifestation of a neuromuscular disorder, frequently associated with non-compaction [8]. Was the patient investigated for neuromus-cular disorders by a neurologist? Did she present with any other feature of a neuromuscular disorder, ...

Metabolic syndrome: to be or not to be?

Early repolarization syndrome- to be or not to be benign.

The early repolarization syndrome, particular electrocardiographic aspect defined as J point and concave ST segment elevation, interpreted by electrophysiologists as benign for over five decades, caused over the past three years many controversies. The trigger for controversy were the results of several, mostly retrospective, studies concluding that individuals with early repolarization syndrom...